Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity linked to bortezomib, a proteasome inhibitor Utilized in the therapy of numerous myeloma. Its synthesis or analyze is crucial for making sure the purity and basic safety with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug used in the therapy of prostate most cancers by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-10-one): A critical compound while in the synthesis of imatinib, a drug that targets specific different types of most cancers, together with Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats different cancers such as breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are definitely intermediates from the synthesis of gemcitabine, an anti-cancer drug. Their review is important for optimizing the production system and guaranteeing high purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is utilised to take care of breast cancer, and these intermediates are linked to its generation.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the cure of breast cancer. A variety of intermediates assist in GeMcitabine Intermediate 8 the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug productive in treating cancers which include ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the cure of colorectal cancer and compact mobile lung cancer.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the (S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4 synthesis of adamantane derivatives, that have numerous programs, which includes antiviral Attributes.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for form two diabetes that inhibits the enzyme DPP-four to regulate blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, which are Utilized in foodstuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate two: A precursor in the synthesis of canagliflozin, a medication used to handle form two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).